José M García Fernández Selected Research

5N,6S- (N'- butyliminomethylidene)- 6- thio- 1- deoxygalactonojirimycin

3/2013

A bicyclic 1-deoxygalactonojirimycin derivative as a novel pharmacological chaperone for GM1 gangliosidosis.

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José M García Fernández Research Topics

Disease

9	Gaucher Disease (Gaucher's Disease) 01/2017 - 11/2009
4	Neoplasms (Cancer) 12/2021 - 02/2010
3	Inflammation (Inflammations) 12/2021 - 05/2010
3	Infections 07/2020 - 02/2010
2	Glioblastoma (Glioblastoma Multiforme) 01/2021 - 01/2017
2	Breast Neoplasms (Breast Cancer) 03/2020 - 08/2010
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 05/2010 - 01/2010
1	Tay-Sachs Disease 12/2022
1	Leishmaniasis 12/2021
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2021
1	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2021
1	Gliosis 01/2021
1	Rare Diseases (Rare Disease) 07/2019
1	Conjoined Twins (Siamese Twins) 07/2019
1	Peritoneal Neoplasms 10/2017
1	Ascites 10/2017
1	Prostatic Neoplasms (Prostate Cancer) 01/2017
1	Neurologic Manifestations (Neurological Manifestations) 06/2015
1	Mitochondrial Diseases (Mitochondrial Disease) 06/2015
1	Human Influenza (Influenza) 01/2015
1	Pathologic Processes 01/2015
1	Fabry Disease (Fabry's Disease) 07/2014
1	Adenocarcinoma 11/2013
1	GM1 Gangliosidosis (Gangliosidosis GM1) 03/2013
1	Mucopolysaccharidosis IV (Morquio Syndrome) 03/2013
1	Edema (Dropsy) 01/2011
1	Colitis 05/2010
1	Metabolic Diseases (Metabolic Disease) 02/2010
1	Dehydration (Water Stress) 02/2010
1	Crohn Disease (Crohn's Disease) 01/2010

Drug/Important Bio-Agent (IBA)

7	Glucosylceramidase (Glucocerebrosidase)IBA 01/2017 - 11/2009
5	GlucosidasesIBA 12/2014 - 11/2010
4	CyclodextrinsIBA 10/2017 - 04/2014
3	Pharmaceutical PreparationsIBA 01/2021 - 01/2010
3	AcidsIBA 04/2014 - 11/2010
2	GlycolipidsIBA 01/2021 - 05/2019
2	VaccinesIBA 07/2020 - 03/2020
2	DNA (Deoxyribonucleic Acid)IBA 07/2019 - 11/2013
2	Surface-Active Agents (Surfactants)IBA 07/2019 - 01/2017
2	GlycosidesIBA 01/2015 - 08/2012
2	OligosaccharidesIBA 01/2015 - 02/2010
2	migalastatIBA 07/2014 - 03/2013
2	GalactosidasesIBA 07/2014 - 03/2013
2	Glucosylceramides (Glucocerebrosides)IBA 04/2014 - 06/2011
2	Proteins (Proteins, Gene)FDA Link 06/2011 - 11/2009
2	FructoseIBA 05/2010 - 02/2010
1	EnzymesIBA 12/2022
1	Hexosaminidase A (Hex A)IBA 12/2022
1	Hexosaminidases (Hexosaminidase)IBA 12/2022
1	NitrogenIBA 12/2021
1	SulfurIBA 12/2021
1	SeleniumIBA 12/2021
1	LipidsIBA 12/2021
1	sulfoxideIBA 01/2021
1	Retinaldehyde (Retinal)IBA 01/2021
1	Peptides (Polypeptides)IBA 07/2020
1	Immunoglobulin G (IgG)IBA 03/2020
1	Tn antigenIBA 03/2020
1	AntibodiesIBA 03/2020
1	CarbohydratesIBA 03/2020
1	DisaccharidesIBA 07/2019
1	Tyr sulfate(1)- enkephalinamide-Leu (LETS)IBA 07/2019
1	TrehaloseIBA 07/2019
1	1- dodecylsulfonyl- 5N,6O- oxomethylidenenojirimycinIBA 05/2019
1	LipopolysaccharidesIBA 05/2019
1	MannosidesIBA 05/2019
1	Interleukin-6 (Interleukin 6)IBA 05/2019
1	Toll-Like Receptors (Toll-Like Receptor)IBA 05/2019
1	Toll-Like Receptor 4IBA 05/2019
1	Small Interfering RNA (siRNA)IBA 10/2017
1	Docetaxel (Taxotere)FDA Link 01/2017
1	NucleotidesIBA 01/2017
1	Calixarenes (Calixarene)IBA 01/2017
1	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2015
1	coenzyme Q10 (CoQ10)IBA 06/2015
1	Ambroxol (Mucosolvan)IBA 01/2015
1	Mannose (D-Mannose)IBA 01/2015
1	Biological ProductsIBA 01/2015
1	Folic Acid (Vitamin M)FDA LinkGeneric 11/2013
1	LigandsIBA 03/2013
1	5N,6S- (N'- butyliminomethylidene)- 6- thio- 1- deoxygalactonojirimycinIBA 03/2013
1	anthrax toxin (anthrax lethal factor)IBA 01/2011
1	AntigensIBA 01/2011
1	alpha-Glucosidases (Acid Maltase)IBA 08/2010
1	castanospermineIBA 08/2010
1	Glycoproteins (Glycoprotein)IBA 08/2010
1	Trinitrobenzenesulfonic AcidIBA 05/2010
1	Sucrose (Saccharose)IBA 05/2010
1	5-hydroxymethylfurfural (hydroxymethylfurfural)IBA 02/2010
1	SugarsIBA 02/2010
1	AntioxidantsIBA 01/2010
1	N-nonyl-1-deoxynojirimycinIBA 11/2009

Therapy/Procedure

2	Therapeutics 07/2019 - 06/2011
1	Cytoreduction Surgical Procedures 10/2017
1	Drug Therapy (Chemotherapy) 10/2017
1	Enzyme Replacement Therapy 06/2015
1	Oral Administration 03/2013